Development of a Production and Transport Vector for a Chimeric Biopesticide in the Treatment of Zebra and Quagga Mussels

Project ID: 22061
Principal Investigator: Kevin Kelly
Research Topic: Invasive Species
Funded Fiscal Years: 2022, 2023 and 2024
Keywords: None

Research Question

Can an immunotoxin-based biopesticide be produced and transported large scale using commercially available wild type Chlamydomonas production vectors?

Chlamydomonas culturing for the purpose of recombinant protein production is well studied and low cost compared to other microalgae system. Identified biopesticide candidates produced based on mAbs discovered by Reclamation and shared during a 3 year collaboration with EQO will be cloned into wild type Chlamydomonas production vectors for scaled production and transport vector for the treatment of zebra and quagga mussels in open bodies of water.

Need and Benefit

There are currently no other biopesticides utilizing immunotoxin technology for the remediation of aquatic nuisance species. The successful development of a chimeric biopesticide has been ongoing for several years in collaboration with EQO. This proposal describes the next phase - the development of a biopesticide production and transport vector which is necessary for large-scale treatment of Dreissenid mussels in water bodies. A draft three-year interim report is available for review.

Contributing Partners

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Research Products

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Last Updated: 6/22/20